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But efficacy is only one variable in the decision

The initial and most noticeable side effects are often nausea and a significant loss of appetite

Bibcode:2006Txcn...47..288C

Its effects on appetite suppression reduce body weight, and significant weight loss effects kick in gradually but mostly appear from 3 months onwards with sustained reductions reaching far up beyond the 4 month mark even if usage remains constant throughout these periods, without further lower doses being required at any given point

Maintaining muscle mass supports metabolic health and helps preserve resting energy expenditure during weight loss